- **Born:** March 18, 1782 in Abbeville District, [[South Carolina]] - **Parents:** Patrick Calhoun (Scots-Irish immigrant) and Martha Caldwell Calhoun - **Spouse:** Floride Bonneau Calhoun (first cousin once removed) - **Children:** Andrew Pickens Calhoun, Floride Pure Calhoun (died in infancy), Jane Calhoun (died in infancy), Anna Maria Calhoun, Elizabeth Calhoun (died in infancy), Patrick Calhoun, John Caldwell Calhoun Jr., Martha Cornelia Calhoun, James Edward Calhoun, William Lowndes Calhoun - **Died:** March 31, 1850 in [[Washington, D.C.]] - **Highest Office:** 7th Vice President of the [[United States of America (USA)]] (1825-1832) - **Other Notable Positions:** U.S. Representative, Secretary of War, U.S. Senator, Secretary of State - **Party Affiliation:** Democratic-Republican Party (later Democratic Party) - **Historical Note:** Ardent defender of slavery and states' rights who developed the doctrine of nullification, arguing states could void federal laws they deemed unconstitutional. First Vice President to resign from office (1832). His political theories on states' rights heavily influenced the South's path toward secession and the Civil War.